Searchable abstracts of presentations at key conferences in endocrinology

ea0081ep587 | Endocrine-Related Cancer | ECE2022

Poor outcome of systemic therapy in secondary high-grade pancreatic neuroendocrine tumors

Mollazadegan Kazhan , Skogseid Britt , Botling Johan , AEkerstrom Tobias , Eriksson Barbro , Welin Staffan , Anders Sundin , Crona Joakim

Introduction: Longitudinal changes in pancreatic neuroendocrine tumor (panNET) cell proliferation correlate with fast disease progression and poor prognosis. The optimal treatment strategy for secondary panNET grade (G)3, that has progressed from a previous low- or intermediate-grade to high-grade panNET G3 is currently unknown. Methods: This was a single center retrospective cohort study, aimed to characterize treatment patterns and outcomes among patie...

ea0099rc7.1 | Rapid Communications 7: Endocrine-related Cancer | ECE2024

PRAP study - Partial versus radical adrenalectomy for hereditary pheochromocytomas

Xu Kai , Langenhuijsen Johannes , Vietor Charlotte , Feelders Richard , van Ginhoven Tessa , Elhassan Yasir , Bioletto Fabio , Parasiliticaprino Mirko , Zandee Wouter , Kruijff Schelto , AEkerstrom Tobias , Pamporaki Christina , Bechmann Nicole , Lussey-Lepoutre Charlotte , Canu Letizia , Steenaard Rebecca , Driessens Natacha , Velema Marieke , Dreijerink Koen , Engelsman Anton , Timmers Henri , de Laat Marieke

Introduction: Pheochromocytoma, a rare catecholamine-secreting adrenal tumor, can cause hypertension and life-threatening complications. Hereditary cases have an increased risk of developing bilateral disease. Standard treatment involves radical adrenalectomy, leading to adrenal insufficiency in bilateral cases. Partial adrenalectomy aims to preserve adrenal function but has higher recurrence rates. This study compares outcomes of partial vs radical adrenalectomy in hereditary...